Oral free communication 3

Oral free communication 3

Journal of Affective Disorders 91S (2006) S45 – S46 www.elsevier.com/locate/jad Oral free communication 3 FC3.1 Name Address Email Authors Affiliatio...

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Journal of Affective Disorders 91S (2006) S45 – S46 www.elsevier.com/locate/jad

Oral free communication 3 FC3.1 Name Address Email Authors Affiliations

Conflict Abstract ID Type Title Keywords Abstract

Mr Yodok Lustenberger Département de Psychiatrie–CHUV UREP Site de Cery 108 Switzerland yodok.l[email protected] Y. Lustenberger, S. Rothen, F. Ferrero, M. Preisig Hôpitaux Universitaires de Genève, Service de psychiatrie adulte, Belle-Idée, Chemin du Petit Bel-Air 2, 1225 CHENE–BOURG; and Hospices–CHUV, Département de Psychiatrie, Unité de Recherche en Epidémiologie et Psychopathologie (UREP), Site de Cery, 10 No AB100 Both Parental bonding attitudes of bipolars and unipolar depressives as assessed by parent and offspring: Influence of present mood state. Parental bonding; Mood disorders Aims: The objective of the present paper was to assess associations between current and remitted parental mood disorder episodes and parenting attitudes, as reported by both parents and their offspring. Background: Methods: In a family study on mood disorders, we collected clinical information on treated probands and their children. The sample included 33 bipolar, 27 unipolar depressive, and 28 control probands as well as their 122 9 to 17 year-old children. Diagnostic assignment was based on a best estimate procedure including semi-structured interviews, medical records and family history information. The proband's parenting attitudes were measured using the Parental Bonding Instrument. Analyses were based on multiple regression models with adjustment for sex and age. Results: Compared to controls, remitted bipolars provided lower Care towards the child, according to parent and offspring report. This was even more pronounced when remission followed a manic rather than a depressive episode. Moreover, currently depressed bipolars described themselves as providing more Encouragement of Freedom compared to controls. In contrast, currently depressed unipolars did not differ from controls in their description of their parenting attitudes. However, they were described by their children as providing decreased levels of Denial of Autonomy and increased levels of Encouragement of Freedom. Conclusion: Our data support parental attitudes of bipolars that differ more from those of controls in remission, as compared to current depressive states. In contrast, unipolar depressives may reveal parenting attitudes that differ more from those of controls during current depression than in remission.

FC3.2 Name Address Email Authors Affiliations

Abstract ID Title

Sagar V. Parikh Dept. of Psychiatry, Toronto Western Hospital, 399 Bathurst St., Toronto, ON, M5T 2S8, Canada. [email protected] Sagar V. Parikha, Vytas Velyvisb, Lakshmi Yathamc, Serge Beaulieud, Pablo Cervantesd, Glenda McQueene, Irene Siotise, David Streinera, Ari Zaretskya a University of Toronto, Toronto, Ontario, Canada, bCentre for Addiction and Mental Health, Toronto, Ontario, Canada, cUniversity of British Columbia, Vancouver, BC, Canada, dMcGill University, Montreal, Quebec, Canada, eMcMaster University, Hamilton, Ontario, Canada ABE12 Coping styles in prodromes of bipolar mania


S46 Abstract

Oral free communication 3 Objective: To examine the Coping Inventory for Prodromes of Mania (CIPM) (1) in bipolar disorder (BD) both for validity and utility in understanding coping styles as a key mechanism in the efficacy of psychosocial interventions. The CIPM is organized into four factors of coping including: stimulation reduction (SR), problem-oriented coping (PR), seeking professional help (SPH), denial and blame (DB). Method: 203 bipolar patients, recruited from across Canada for a clinical trial comparing psychoeducation to CBT, completed a CIPM at baseline. CIPM psychometric properties and its relationship to demographic and clinical factors, dysfunctional attitudes, and mood symptoms were examined. Finally, post hoc coping profiles were generated by BD subtype (I vs. II). Results: Internal consistencies and subscale means were commensurate with the original validation study. Neither demographic/ clinical characteristics nor mood symptoms showed any particular relationship with the CIPM; however, the CIPM was related to dysfunctional attitudes. Clear differences in coping also emerged between BD I and BD II subjects. BD I tended to use a wider range of coping strategies and scored highly on the SPH factor as compared to BD II subjects. BD II participants preferred to use DB and PR, but were less likely to use SPH and SR. Conclusion: The CIPM appears to be a valid measure of coping despite indications that two subscales demonstrated less than adequate internal consistency. Canadian norms appear consistent with a previously published study. Coping style preferences appear to differ according to bipolar subtype. This study has been funded in part by the Canadian Institutes of Health Research and the Stanley.

FC3.3 Name Authors Conflict Abstract ID Title Abstract

M. Preisig M. Preisig, F. Ferrero No ABE35 Bipolar I disorder with and without attention-deficit/hyperactivity disorder (ADHD) Aims: 1) To determine the strength of the association between bipolar-I disorder and ADHD; 2) to study the impact of comorbid ADHD on the course and magnitude of familial aggregation of bipolar disorder and 3) to assess the mechanism of the association between the two disorders by examining the patterns of familial aggregation of the two disorders. Background: Although several studies found mania to be associated with ADHD, the clinical consequences and nature of this association remain unclear. Methods: Analyses were based on a family study including 128 bipolar-I, 89 alcohol or heroin dependent probands and 97 controls, as well as 482 interviewed adult first-degree relatives and 307 minor offspring. Diagnostic assignment was based on a best estimate procedure including semi-structured interviews, medical records and family history information. Results: 1) A strong association between bipolar-I disorder and a lifetime history of ADHD was confirmed in both, probands and relatives; 2) a history of ADHD in bipolar-I probands was associated with the history of other comorbid childhood disorders such as oppositional defiant and overanxious disorder but not with the course of bipolar disorder; relatives of bipolars with comorbid ADHD were at an increased risk for bipolar-I disorder, generalized anxiety disorder and alcohol dependence; 3) a strong degree of familial aggregation was observed for bipolar-I disorder but not for ADHD; there was no evidence of crossaggregation between bipolar-I disorder and ADHD. Conclusions: Although bipolar-I disorder with and without a lifetime history of ADHD reveal a similar course, the increased risk of bipolar disorder in the relatives of bipolar probands with a history of ADHD and the absence of cross-aggregation between the two disorders suggest that ADHD could be a marker of a particularly severe form of bipolar disorder with an increased genetic loading.